Interim head coach Lee Carsley takes charge of the senior side for the penultimate time, just a month after the Three Lions were beaten at Wembley by the same opponents.
That shock result leaves England needing to beat Greece to stand any realistic chance of finishing top of League B Group 2 ahead of Sunday’s showdown with Ireland.
Top spot will earn automatic promotion league to League A, while second place will earn a promotion play-off spot. A draw tonight will be enough to confirm a top-two finish.
Carsley has this week had his hands full juggling several withdrawals from his squad, which saw eight bow out on Monday evening.
It has, however, created space for the likes of Morgan Rogers to earn a first senior call-up, and others the chance to impress ahead of the January arrival of incoming permanent manager Thomas Tuchel.
Where to watch Greece vs England
TV channel: In the UK, the game will be televised live on ITV1, with coverage starting at 7pm GMT.
Live stream: Fans can catch the contest live online via the ITVX app and website.