Nick Grant, UEA University and College Union co-chair said the cuts “jeopardise not only the careers of our colleagues, but the reputation and future success of the university”.
He said that in 2023, when a £40m deficit was first announced by the UEA, more than 400 staff lost their jobs through voluntary severance or redundancy.
“UEA will not survive or thrive with fewer hardworking staff,” he said.
He said the cuts would be felt across all its four faculties, including sciences and health as well as arts and humanities.
He expected those delivering student support, digital and tech staff supporting academic staff, library staff and those helping academics to win bids and bring in revenue would be among those affected.
Accepting most universities were struggling financially, Mr Grant said the UEA was in a worse position.
“We are an outlier in terms of the cuts we’ve seen recently, in terms of the cuts that we are going to be potentially seeing again,” he said.
“I think staff and students are potentially being thrown under a bus because of the historic mismanagement of the institution.”