Rico Lewis is suspended for Manchester City following his red card against Crystal Palace.
Manager Pep Guardiola has only three senior defenders available and says he may need to use midfielders as makeshift full-backs or wing-backs.
Rodri, Oscar Bobb, Nathan Ake, John Stones and Manuel Akanji are still injured, though Phil Foden and Mateo Kovacic returned to the matchday squad against Juventus in midweek and could make their comebacks on Sunday.
Manchester United head coach Ruben Amorim has reported no fresh injury concerns.
Jonny Evans has resumed training and may come back into contention but Luke Shaw remains sidelined.