Diversions will take place on the c2c network, connecting London to south Essex, from Monday to Thursday (September 16-19) and Sunday (September 22).
Starting from Monday, planned engineering work will take place between Southend Central and Shoeburyness.
The work will start at 11.55pm, with services starting and terminating at Leigh or Southend Central.
A rail replacement bus service has been arranged to operate between these stations.
Commuters are advised that the evening works could have a knock-on effect to their travel the following mornings, with some services potentially starting at alternative locations according to c2c.
Southend Central, Southend East, Thorpe Bay, and Shoeburyness stations are expected to be affected by the works from Monday to Thursday.
c2c has warned service users that until 2.45pm, the Basildon line service cannot run to Barking or beyond.
Instead, the services will start and terminate at Upminster, missing out Barking, Stratford and Liverpool Street stations.
Ticket acceptance has been arranged on District line services between Tower Hill, West Ham, Barking, and Upminster, and on DLR services between Tower Gateway, Limehouse, and Stratford/West Ham.
From 2.45pm, services will resume but will be diverted to Fenchurch Street as work continues.
Past this time, services will call additionally at West Ham, missing Stratford. Tickets will be accepted on the Jubilee line between West Ham and Stratford.
On the Ockendon line, engineering work will be conducted between Fenchurch Street and Grays via Rainham.
Until 2.45pm, line users should note that services cannot run to Barking or beyond.
The services will start and terminate at Upminster, and won’t be calling at Barking, West Ham, Limehouse, or Fenchurch Street.
Valid tickets will be accepted on District line services between Tower Hill, West Ham, Barking, and Upminster, and DLR on services between Tower Gateway, Limehouse, and West Ham.
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Rail replacement services have been organised for the Rainham line on the Sunday as a result of works between Fenchurch Street and Grays via Rainham.
Trains will not run until 2.25pm and a rail replacement bus will serve between Upminster, Rainham, Purfleet, and Grays.
Passengers looking to travel to Dagenham Dock will have their tickets accepted on the EL2 and 287 TfL bus services.