The event will take place on the flagship Queen Mary 2, during a voyage from New York to Southampton from October 31 to November 7.
Siriano, a notable figure in the fashion world, launched his collection in 2008 after studying in London under Vivienne Westwood and Alexander McQueen.
Katie McAlister, president of Cunard said: “Christian Siriano is a true visionary, and we are delighted to have him lead our 2025 Transatlantic Fashion Week. His bold old-school glamour mirrors Cunard’s own blend of timeless elegance and modern luxury.
“Our Fashion Week voyages have become must-attend events, attracting celebrated designers from around the world, and there’s no better venue for such an occasion than Queen Mary 2 – the world’s most glamourous ocean liner.”
Siriano said: “It’s a wonderful opportunity to be part of Cunard’s iconic Transatlantic Fashion Week and I am excited to headline next year’s voyage. What a unique way to showcase my designs that celebrate both the heritage of fashion as well as its future. I can’t wait to show guests on board a fabulous and once-in-a-lifetime experience!”
His designs have been worn by global stars such as Lady Gaga, Oprah, and Julia Roberts, as well as Michelle Obama and Kamala Harris.
Now in its 15th year, the Siriano Atelier continues to celebrate beauty and diversity.
During the voyage, Siriano will showcase some of his archived designs in an exclusive runway show in the Queens Room.
He will also participate in a Q&A session in the Royal Court Theatre and meet guests personally at book signings.
The Transatlantic Fashion Week, now in its fifth year, is a celebration of fashion, set against the backdrop of Cunard’s flagship.
Prices for the voyage start from £899 per person based on two sharing a Britannia Balcony stateroom.
Since its start in 2016, the event has featured designers such as Dame Zandra Rhodes, Julien Macdonald, Virginia Bates, and Stephen Jones OBE.