After twice defending his crown, Prince was beaten when he fought Dariusz Michalczewski, external for the world title in Oberhausen, Germany in September 1998.
In 2006, his 15-year-old son Kiyan was murdered by a fellow teenager while trying to break up a fight.
Kiyan was a talented footballer, who had joined the academy of Championship side Queens Park Rangers when he was 13.
Reflecting on his son’s death, Prince said: “I don’t think we are built for news like that.
“I wanted to do bad things. The pain is indescribable. Boxing is easy – this was a different fight.
“The only control I really have is how I deal with the situations I find myself in. After Kiyan died, I thought, ‘why don’t I do this for my son?'”
Prince created the Kiyan Prince Foundation, which has reached more than 100,000 children through its programmes, life coaching and motivational talks.
He was made an OBE in the 2019 New Year’s Honours list for his work to combat knife crime.
The foundation was awarded the naming rights to QPR’s Loftus Road in 2019 following a public vote, and has been supported by current and former footballers including Les Ferdinand, Jamie Redknapp and Charlie Austin.
“The club was heavily involved in supporting Mark,” former QPR and England striker Ferdinand told BBC Sport.
“What he brings is honesty and truth. In Mark, these boys can see themselves. They come from where he did.”
This year marks the 25th year of the Helen Rollason Award.
Former javelin world record holder and Olympic medallist Fatima Whitbread won the award in 2023, and previous recipients include rugby league legend Rob Burrow, Scotland rugby union great Doddie Weir, Hillsborough campaigner Anne Williams, football fan Bradley Lowery and racing driver Billy Monger.