Across the country, the first polls will close at 18:00 EST (23:00 GMT) on Tuesday evening and the last polls will close at 01:00 EST (06:00 GMT) early on Wednesday.
But this race is expected to come down to results from the seven swing states – Arizona, Georgia, Michigan, Nevada, North Carolina, Pennsylvania and Wisconsin.
19:00 EST (00:00 GMT) – Polls close in Georgia and five other states, and partially in two more states. This is also when US TV networks are likely to begin making their first calls of the night, in less competitive states like Kentucky.
19:30 EST (00:30 GMT) – Polls close across three states, including North Carolina, where Harris is hoping to end a string of losses for Democratic presidential candidates since 2008.
20:00 EST (01:00 GMT) – Polls close in Pennsylvania, 15 other states and the District of Columbia, as well as partially in Michigan and four other states.
21:00 EST (02:00 GMT) – All remaining polls close in Michigan. Voting will also end in Arizona, Wisconsin and 12 other states.
22:00 EST (03:00 GMT) – Polls close across Nevada and two other states, and partially in two others.